Biology:CDP-paratose synthase

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CDP-paratose synthase
Identifiers
EC number1.1.1.342
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

CDP-paratose synthase (EC 1.1.1.342, rfbS (gene)) is an enzyme with systematic name CDP-alpha-D-paratose:NADP+ 4-oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

CDP-alpha-D-paratose + NADP+ [math]\displaystyle{ \rightleftharpoons }[/math] CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+

This enzyme participates in synthesis of paratose and tyvelose.

References

  1. "Identification and sequence of rfbS and rfbE, which determine antigenic specificity of group A and group D salmonellae". Journal of Bacteriology 171 (10): 5694–701. October 1989. PMID 2793833. 
  2. "Mechanistic studies of the biosynthesis of paratose: purification and characterization of CDP-paratose synthase". Biochemistry 37 (14): 4935–45. April 1998. doi:10.1021/bi9725529. PMID 9538012. 

External links