Biology:Caspase 13
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Short description: Bovine protein
 Generic protein structure example |
Caspase 13 or ERICE ("evolutionarily related interleukin-1β converting enzyme") is a protein that was identified in cattle. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. Although this enzyme was originally reported as a human caspase that could be activated by caspase 8,[1] later studies confirmed the gene identified for caspase 13 came from bovine origin, and is the likely orthologue of human caspase 4.[2][3]
References
- ↑ "ERICE, a novel FLICE-activatable caspase". J. Biol. Chem. 273 (25): 15702–7. 1998. doi:10.1074/jbc.273.25.15702. PMID 9624166.
- ↑ "Evidence that caspase-13 is not a human but a bovine gene". Biochem. Biophys. Res. Commun. 285 (5): 1150–4. 2001. doi:10.1006/bbrc.2001.5315. PMID 11478774.
- ↑ NCBI Sequence Viewer v2.0
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