Biology:Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase

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Short description: Class of enzymes
Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase
Identifiers
EC number2.4.1.254
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase (EC 2.4.1.254, BpUGT94B1, UDP-glucuronic acid:anthocyanin glucuronosyltransferase, UDP-glucuronic acid:anthocyanidin 3-glucoside 2'-O-beta-glucuronosyltransferase, BpUGAT, UDP-D-glucuronate:cyanidin-3-O-beta-glucoside 2-O-beta-glucuronosyltransferase) is an enzyme with systematic name UDP-D-glucuronate:cyanidin-3-O-beta-D-glucoside 2-O-beta-D-glucuronosyltransferase.[1][2] This enzyme catalyses the following chemical reaction

UDP-D-glucuronate + cyanidin 3-O-beta-D-glucoside [math]\displaystyle{ \rightleftharpoons }[/math] UDP + cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside

The enzyme is highly specific for cyanidin 3-O-glucosides and UDP-D-glucuronate.

References

  1. "UDP-glucuronic acid:anthocyanin glucuronosyltransferase from red daisy (Bellis perennis) flowers. Enzymology and phylogenetics of a novel glucuronosyltransferase involved in flower pigment biosynthesis". The Journal of Biological Chemistry 280 (2): 899–906. January 2005. doi:10.1074/jbc.m410537200. PMID 15509561. 
  2. "Catalytic key amino acids and UDP-sugar donor specificity of a plant glucuronosyltransferase, UGT94B1: molecular modeling substantiated by site-specific mutagenesis and biochemical analyses". Plant Physiology 148 (3): 1295–308. November 2008. doi:10.1104/pp.108.128256. PMID 18829982. 

External links