Biology:Cyclohexanol dehydrogenase
From HandWiki
| cyclohexanol dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.245 | ||||||||
| CAS number | 63951-98-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a cyclohexanol dehydrogenase (EC 1.1.1.245) is an enzyme that catalyzes the chemical reaction
- cyclohexanol + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] cyclohexanone + NADH + H+
Thus, the two substrates of this enzyme are cyclohexanol and NAD+, whereas its 3 products are cyclohexanone, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cyclohexanol:NAD+ oxidoreductase. This enzyme participates in caprolactam degradation.
References
- "Enzyme-reactions involved in anaerobic cyclohexanol metabolism by a denitrifying Pseudomonas species". Arch. Microbiol. 152 (3): 273–279. 1989. doi:10.1007/BF00409663. PMID 2505723.
- "The metabolism of cyclohexanol by Acinetobacter NCIB 9871". Eur. J. Biochem. 60 (1): 1–7. 1975. doi:10.1111/j.1432-1033.1975.tb20968.x. PMID 1261.
- "Isolation and Characterization of a Cyclohexane-Metabolizing Xanthobacter sp". Appl. Environ. Microbiol. 49 (5): 1282–1289. 1985. PMID 16346796.
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