Biology:D-xylose reductase
From HandWiki
| D-xylose reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.307 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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D-xylose reductase (EC 1.1.1.307, XylR, XyrA, msXR, dsXR, monospecific xylose reductase, dual specific xylose reductase, NAD(P)H-dependent xylose reductase, xylose reductase) is an enzyme with systematic name xylitol:NAD(P)+ oxidoreductase.[1][2][3][4][5][6][7][8] This enzyme catalyses the following chemical reaction
- REDIRECT Template:Chemical reaction
Xylose reductase catalyses the initial reaction in the xylose utilization pathway. The enzyme can use nicotinamide adenine dinucleotide (NADH) or nicotinamide adenine dinucleotide phosphate (NADPH) as its cofactor.[9]
References
- ↑ "NAD(P)H-dependent aldose reductase from the xylose-assimilating yeast Candida tenuis. Isolation, characterization and biochemical properties of the enzyme". The Biochemical Journal 326 ( Pt 3) (Pt 3): 683–92. September 1997. doi:10.1042/bj3260683. PMID 9307017.
- ↑ "Multiple forms of xylose reductase in Candida intermedia: comparison of their functional properties using quantitative structure-activity relationships, steady-state kinetic analysis, and pH studies". Journal of Agricultural and Food Chemistry 51 (27): 7930–5. December 2003. doi:10.1021/jf034426j. PMID 14690376.
- ↑ "[The activity of xylose reductase and xylitol dehydrogenase in yeasts]". Mikrobiologiia 72 (4): 466–9. 2003. PMID 14526534.
- ↑ "Purification, crystallization and preliminary X-ray crystallographic analysis of xylose reductase from Candida tropicalis". Acta Crystallographica Section F 65 (Pt 4): 419–21. April 2009. doi:10.1107/S1744309109008719. PMID 19342796.
- ↑ "Properties of the NAD(P)H-dependent xylose reductase from the xylose-fermenting yeast Pichia stipitis". The Biochemical Journal 226 (3): 669–77. March 1985. doi:10.1042/bj2260669. PMID 3921014.
- ↑ "Xylose reductase from the thermophilic fungus Talaromyces emersonii: cloning and heterologous expression of the native gene (Texr) and a double mutant (TexrK271R + N273D) with altered coenzyme specificity". Journal of Biosciences 34 (6): 881–90. December 2009. doi:10.1007/s12038-009-0102-7. PMID 20093741.
- ↑ "Cloning and characterization of the xyl1 gene, encoding an NADH-preferring xylose reductase from Candida parapsilosis, and its functional expression in Candida tropicalis". Applied and Environmental Microbiology 69 (10): 6179–88. October 2003. doi:10.1128/AEM.69.10.6179-6188.2003. PMID 14532079. Bibcode: 2003ApEnM..69.6179L.
- ↑ "Heterologous expression, purification, and characterization of a highly active xylose reductase from Neurospora crassa". Applied and Environmental Microbiology 71 (3): 1642–7. March 2005. doi:10.1128/AEM.71.3.1642-1647.2005. PMID 15746370. Bibcode: 2005ApEnM..71.1642W.
- ↑ Enzyme 1.1.1.307 at KEGG Pathway Database.
External links
- D-xylose+reductase at the US National Library of Medicine Medical Subject Headings (MeSH)
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