Biology:Diiodophenylpyruvate reductase
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diiodophenylpyruvate reductase | |||||||||
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Identifiers | |||||||||
EC number | 1.1.1.96 | ||||||||
CAS number | 37250-31-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a diiodophenylpyruvate reductase (EC 1.1.1.96) is an enzyme that catalyzes the chemical reaction
- 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + NADH + H+
Thus, the two substrates of this enzyme are 3-(3,5-diiodo-4-hydroxyphenyl)lactate and NAD+, whereas its 3 products are 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-(3,5-diiodo-4-hydroxyphenyl)lactate:NAD+ oxidoreductase. Other names in common use include aromatic alpha-keto acid, KAR, and 2-oxo acid reductase.
References
- "Isolation and properties of aromatic alpha-keto acid reductase". J. Biol. Chem. 241 (6): 1340–4. 1966. PMID 5935348.
Original source: https://en.wikipedia.org/wiki/Diiodophenylpyruvate reductase.
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