Biology:Flavonol-3-O-glycoside glucosyltransferase

From HandWiki
Short description: Class of enzymes
Flavonol-3-O-glycoside glucosyltransferase
Identifiers
EC number2.4.1.240
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

In enzymology, a flavonol-3-O-glycoside glucosyltransferase (EC 2.4.1.240) is an enzyme that catalyzes the chemical reaction

UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside [math]\displaystyle{ \rightleftharpoons }[/math] UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside

Thus, the two substrates of this enzyme are UDP-glucose and flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside, whereas its 3 products are UDP, flavonol, and 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:flavonol-3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 2-O-beta-D-glucosyltransferase.

References

  • "Isolation and partial characterization of three glucosyl transferases involved in the biosynthesis of flavonol triglucosides in Pisum sativum L". Arch. Biochem. Biophys. 213 (2): 434–43. 1982. doi:10.1016/0003-9861(82)90569-0. PMID 6462109.