Biology:GDP-mannose:cellobiosyl-diphosphopolyprenol alpha-mannosyltransferase
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Short description: Class of enzymes
| GDP-mannose:cellobiosyl-diphosphopolyprenol alpha-mannosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.252 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
GDP-mannose:cellobiosyl-diphosphopolyprenol alpha-mannosyltransferase (EC 2.4.1.252, GumH, AceA, alpha1,3-mannosyltransferase AceA) is an enzyme with systematic name GDP-mannose:D-Glc-beta-(1->4)-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol 3-alpha-mannosyltransferase .[1][2][3][4][5] This enzyme catalyses the following chemical reaction
- GDP-mannose + D-Glc-beta-(1->4)-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol [math]\displaystyle{ \rightleftharpoons }[/math] GDP + D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol
In the bacterium Gluconacetobacter xylinus the enzyme is involved in the biosynthesis of the exopolysaccharide acetan.
References
- ↑ "Expression and biochemical characterisation of recombinant AceA, a bacterial alpha-mannosyltransferase". Molecular & General Genetics 261 (6): 933–40. July 1999. doi:10.1007/s004380051040. PMID 10485283.
- ↑ "Identification of essential amino acids in the bacterial alpha -mannosyltransferase aceA". The Journal of Biological Chemistry 275 (51): 40568–75. December 2000. doi:10.1074/jbc.M007496200. PMID 11001941.
- ↑ "Isolation and nucleotide sequence of the GDP-mannose:cellobiosyl-diphosphopolyprenol alpha-mannosyltransferase gene from Acetobacter xylinum". Journal of Bacteriology 178 (16): 4814–21. August 1996. doi:10.1128/jb.178.16.4814-4821.1996. PMID 8759843.
- ↑ "Phytanyl-pyrophosphate-linked substrate for a bacterial alpha-mannosyltransferase". Biochemical and Biophysical Research Communications 272 (1): 290–2. May 2000. doi:10.1006/bbrc.2000.2771. PMID 10872841.
- ↑ Katzen, F.; Ferreiro, D.U.; Oddo, C.G.; Ielmini, M.V.; Becker, A.; Puhler, A.; Ielpi, L. (1998). "Xanthomonas campestris pv. campestris gum mutants: effects on xanthan biosynthesis and plant virulence". J. Bacteriol. 180 (7): 1607–1617. PMID 9537354.
External links
- GDP-mannose:cellobiosyl-diphosphopolyprenol+alpha-mannosyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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