Biology:Galactitol 2-dehydrogenase
From HandWiki
| galactitol 2-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.16 | ||||||||
| CAS number | 9028-23-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a galactitol 2-dehydrogenase (EC 1.1.1.16) is an enzyme that catalyzes the chemical reaction
- galactitol + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] D-tagatose + NADH + H+
Thus, the two substrates of this enzyme are galactitol and NAD+, whereas its 3 products are D-tagatose, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is galactitol:NAD+ 2-oxidoreductase. This enzyme is also called dulcitol dehydrogenase. This enzyme participates in galactose metabolism.
References
- "Polyol dehydrogenases. 3. Galactitol dehydrogenase and D-iditol dehydrogenase". The Biochemical Journal 64 (3): 394–405. November 1956. doi:10.1042/bj0640394. PMID 13373783.
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