Biology:Glucosyl-3-phosphoglycerate synthase
From HandWiki
Short description: Class of enzymes
| Glucosyl-3-phosphoglycerate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.266 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Glucosyl-3-phosphoglycerate synthase (EC 2.4.1.266, GpgS protein, GPG synthase, glucosylphosphoglycerate synthase) is an enzyme with systematic name NDP-glucose:3-phospho-D-glycerate 2-alpha-D-glucosyltransferase.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- NDP-glucose + 3-phospho-D-glycerate [math]\displaystyle{ \rightleftharpoons }[/math] NDP + 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate
The enzyme is involved in biosynthesis of 2-O-(alpha-D-glucopyranosyl)-D-glycerate.
References
- ↑ "Glucosylglycerate biosynthesis in the deepest lineage of the Bacteria: characterization of the thermophilic proteins GpgS and GpgP from Persephonella marina". Journal of Bacteriology 189 (5): 1648–54. March 2007. doi:10.1128/JB.00841-06. PMID 17189358.
- ↑ "Characterization of the biosynthetic pathway of glucosylglycerate in the archaeon Methanococcoides burtonii". Journal of Bacteriology 188 (3): 1022–30. February 2006. doi:10.1128/JB.188.3.1022-1030.2006. PMID 16428406.
- ↑ "Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase". FEMS Microbiology Letters 280 (2): 195–202. March 2008. doi:10.1111/j.1574-6968.2007.01064.x. PMID 18221489.
- ↑ Song, Haiwei, ed (2008). "Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis". PLOS ONE 3 (11): e3748. doi:10.1371/journal.pone.0003748. PMID 19015727. Bibcode: 2008PLoSO...3.3748P.
- ↑ "Preliminary crystallographic analysis of GpgS, a key glucosyltransferase involved in methylglucose lipopolysaccharide biosynthesis in Mycobacterium tuberculosis". Acta Crystallographica Section F 64 (Pt 12): 1121–4. December 2008. doi:10.1107/S1744309108032892. PMID 19052364.
- ↑ Herman, Christophe, ed (2009). "Initiation of methylglucose lipopolysaccharide biosynthesis in mycobacteria". PLOS ONE 4 (5): e5447. doi:10.1371/journal.pone.0005447. PMID 19421329. Bibcode: 2009PLoSO...4.5447K.
External links
- Glucosyl-3-phosphoglycerate+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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