Biology:Glycosaminoglycan galactosyltransferase
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Short description: Class of enzymes
| glycosaminoglycan galactosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.74 | ||||||||
| CAS number | 51004-28-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a glycosaminoglycan galactosyltransferase (EC 2.4.1.74) is an enzyme that catalyzes the chemical reaction
- UDP-galactose + glycosaminoglycan [math]\displaystyle{ \rightleftharpoons }[/math] UDP + D-galactosylglycosaminoglycan
Thus, the two substrates of this enzyme are UDP-galactose and glycosaminoglycan, whereas its two products are UDP and D-galactosylglycosaminoglycan.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:glycosaminoglycan D-galactosyltransferase. This enzyme is also called uridine diphosphogalactose-mucopolysaccharide galactosyltransferase.
References
- "UDP-glucose polysaccharide transferase in the cellular slime mold Dictyostelium discoideum: appearance and disappearance of activity during cell differentiation". Proc. Natl. Acad. Sci. USA 52 (1): 81–87. 1964. doi:10.1073/pnas.52.1.81. PMID 14192661. Bibcode: 1964PNAS...52...81S.
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