Biology:Lactotriaosylceramide beta-1,4-galactosyltransferase

From HandWiki
Short description: Class of enzymes
Lactotriaosylceramide beta-1,4-galactosyltransferase
Identifiers
EC number2.4.1.275
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Lactotriaosylceramide beta-1,4-galactosyltransferase (EC 2.4.1.275, beta4Gal-T4, UDP-galactose:N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide beta-1,4-galactosyltransferase) is an enzyme with systematic name UDP-alpha-D-galactose:N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide 4-beta-D-galactosyltransferase.[1] This enzyme catalyses the following chemical reaction

UDP-alpha-D-galactose + N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide [math]\displaystyle{ \rightleftharpoons }[/math] UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

References

  1. "Cloning of a novel member of the UDP-galactose:beta-N-acetylglucosamine beta1,4-galactosyltransferase family, beta4Gal-T4, involved in glycosphingolipid biosynthesis". The Journal of Biological Chemistry 273 (45): 29331–40. November 1998. doi:10.1074/jbc.273.45.29331. PMID 9792633. 

External links