Biology:Lipopolysaccharide glucosyltransferase I
lipopolysaccharide glucosyltransferase I | |||||||||
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Identifiers | |||||||||
EC number | 2.4.1.58 | ||||||||
CAS number | 9074-00-4 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a lipopolysaccharide glucosyltransferase I (EC 2.4.1.58) is an enzyme that catalyzes the chemical reaction
- UDP-glucose + lipopolysaccharide [math]\displaystyle{ \rightleftharpoons }[/math] UDP + D-glucosyl-lipopolysaccharide
Thus, the two substrates of this enzyme are UDP-glucose and lipopolysaccharide, whereas its two products are UDP and D-glucosyl-lipopolysaccharide.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:lipopolysaccharide glucosyltransferase. Other names in common use include UDP-glucose:lipopolysaccharide glucosyltransferase I, lipopolysaccharide glucosyltransferase, uridine diphosphate glucose:lipopolysaccharide glucosyltransferase, I, and uridine diphosphoglucose-lipopolysaccharide glucosyltransferase. This enzyme participates in lipopolysaccharide biosynthesis and glycan structures - biosynthesis 2.
References
- "Studies of phospholipid-requiring bacterial enzymes. 3. Purification and properties of uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I". J. Biol. Chem. 247 (8): 2614–22. 1972. PMID 4553445.
- "Biosynthesis of bacterial lipopolysaccharide. II. Incorporation of glucose and galactose catalyzed by particulate and soluble enzymes in salmonella". J. Biol. Chem. 239: 2788–2795. 1964. PMID 14217875.
Original source: https://en.wikipedia.org/wiki/Lipopolysaccharide glucosyltransferase I.
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