Biology:Luteolin-7-O-glucuronide 2"-O-glucuronosyltransferase

From HandWiki
Short description: Class of enzymes
luteolin-7-O-glucuronide 7-O-glucuronosyltransferase
Identifiers
EC number2.4.1.190
CAS number115490-51-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a luteolin-7-O-glucuronide 2"-O-glucuronosyltransferase (EC 2.4.1.190) is an enzyme that catalyzes the chemical reaction

UDP-glucuronate + luteolin 7-O-beta-D-glucuronide [math]\displaystyle{ \rightleftharpoons }[/math] UDP + luteolin 7-O-[beta-D-glucuronosyl-(1→2)-beta-D-glucuronide]

Thus, the two substrates of this enzyme are UDP-glucuronate and luteolin 7-O-beta-D-glucuronide, whereas its two products are UDP and luteolin 7-O-(beta-D-glucuronosyl-(1→2)-beta-D-glucuronide).

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucuronate:luteolin-7-O-beta-D-glucuronide 2''-O-glucuronosyltransferase. Other names in common use include uridine diphosphoglucuronate-luteolin 7-O-glucuronide, glucuronosyltransferase, LMT, and UDP-glucuronate:luteolin 7-O-glucuronide-glucuronosyltransferase.

References

  • Schulz M; Weissenbock G (1988). "3 specific UDP-glucuronate-flavone-glucuronosyl-transferases from primary leaves of Secale cereale". Phytochemistry 27 (5): 1261–1267. doi:10.1016/0031-9422(88)80175-4. 
  • "Subcellular localization of luteolin glucuronides and related enzymes in rye mesophyll". Planta 187 (1): 83–8. April 1992. doi:10.1007/bf00201627. PMID 24177970.