Biology:Luteolin 7-O-glucuronosyltransferase

From HandWiki
Short description: Class of enzymes
luteolin 7-O-glucuronosyltransferase
Identifiers
EC number2.4.1.189
CAS number115490-49-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a luteolin 7-O-glucuronosyltransferase (EC 2.4.1.189) is an enzyme that catalyzes the chemical reaction

UDP-glucuronate + luteolin [math]\displaystyle{ \rightleftharpoons }[/math] UDP + luteolin 7-O-beta-D-glucuronide

Thus, the two substrates of this enzyme are UDP-glucuronate and luteolin, whereas its two products are UDP and luteolin 7-O-beta-D-glucuronide.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucuronate:luteolin 7-O-glucuronosyltransferase. Other names in common use include uridine diphosphoglucuronate-luteolin 7-O-glucuronosyltransferase, and LGT.

References

  • "3 specific UDP-glucuronate-flavone-glucuronosyl-transferases from primary leaves of Secale cereale". Phytochemistry 27 (5): 1261–1267. 1988. doi:10.1016/0031-9422(88)80175-4.