Biology:Maltose-transporting ATPase
From HandWiki
Short description: Class of enzymes
| maltose-transporting ATPase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.6.3.19 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a maltose-transporting ATPase (EC 3.6.3.19) is an enzyme that catalyzes the chemical reaction
- ATP + H2O + maltoseout [math]\displaystyle{ \rightleftharpoons }[/math] ADP + phosphate + maltosein
The 3 substrates of this enzyme are ATP, H2O, and maltose, whereas its 3 products are ADP, phosphate, and maltose.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (maltose-importing). This enzyme is a member of the ABC Transporter family.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2AWN and 2AWO.
References
- Higgins CF (1992). "ABC transporters: from microorganisms to man". Annu. Rev. Cell Biol. 8: 67–113. doi:10.1146/annurev.cb.08.110192.000435. PMID 1282354.
- "Membrane topology of MalG, an inner membrane protein from the maltose transport system of Escherichia coli". Mol. Microbiol. 7 (1): 29–38. 1993. doi:10.1111/j.1365-2958.1993.tb01094.x. PMID 8437518.
- "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146 (4): 271–8. 1995. doi:10.1016/0923-2508(96)81050-3. PMID 7569321.
- Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol.. Advances in Microbial Physiology 40: 81–136. doi:10.1016/S0065-2911(08)60130-7. ISBN 9780120277407. PMID 9889977.
- Griffiths JK; Sansom CE. The Transporter Factsbook, Academic Press, San Diego, 1998.
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