Biology:Peroxisome-assembly ATPase
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Short description: Class of enzymes
| Peroxisome-assembly ATPase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.6.4.7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
In enzymology, a peroxisome-assembly ATPase (EC 3.6.4.7) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are ATP and H2O, whereas its two products are ADP and phosphate. Its function is to transport components of the peroxisome in and out of the organelle.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to facilitate cellular and subcellular movement. The systematic name of this enzyme class is ATP phosphohydrolase (peroxisome-assembling). This enzyme is also called peroxisome assembly factor-2.
References
- "AFG1, a new member of the SEC18-NSF, PAS1, CDC48-VCP, TBP family of ATPases". Yeast 8 (9): 787–90. 1992. doi:10.1002/yea.320080912. PMID 1441755. https://zenodo.org/record/1229386.
- T; Fujiki Y; Sakai F; Bogaki A et al. (1995). "Peroxisome assembly factor-2, a putative ATPase cloned by functional complementation on a peroxisome-deficient mammalian cell mutant". Nat. Genet. 11 (4): 395–401. doi:10.1038/ng1295-395. PMID 7493019.
- "The peroxisome biogenesis disorder group 4 gene, PXAAA1, encodes a cytoplasmic ATPase required for stability of the PTS1 receptor". EMBO J. 15 (12): 2914–23. 1996. doi:10.1002/j.1460-2075.1996.tb00654.x. PMID 8670792.
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