Biology:Poly(glycerol-phosphate) alpha-glucosyltransferase

From HandWiki
Short description: Class of enzymes
poly(glycerol-phosphate) alpha-glucosyltransferase
Identifiers
EC number2.4.1.52
CAS number37277-60-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a poly(glycerol-phosphate) alpha-glucosyltransferase (EC 2.4.1.52) is an enzyme that catalyzes the chemical reaction

UDP-glucose + poly(glycerol phosphate) [math]\displaystyle{ \rightleftharpoons }[/math] UDP + O-(alpha-D-glucosyl)poly(glycerol phosphate)

Thus, the two substrates of this enzyme are UDP-glucose and poly(glycerol phosphate), whereas its two products are UDP and O-(alpha-D-glucosyl)poly(glycerol phosphate).

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase. Other names in common use include UDP glucose-poly(glycerol-phosphate) alpha-glucosyltransferase, uridine diphosphoglucose-poly(glycerol-phosphate), and alpha-glucosyltransferase.

References

  • "THE SYNTHESIS OF TEICHOIC ACIDS. 3. GLUCOSYLATION OF POLYGLYCEROPHOSPHATE". J. Biol. Chem. 239: 3187–91. 1964. PMID 14245359.