Biology:Pyranose dehydrogenase (acceptor)

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Pyranose dehydrogenase (acceptor)
Identifiers
EC number1.1.99.29
CAS number190606-21-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Pyranose dehydrogenase (acceptor) (EC 1.1.99.29, pyranose dehydrogenase, pyranose-quinone oxidoreductase, quinone-dependent pyranose dehydrogenase, PDH) is an enzyme with systematic name pyranose:acceptor oxidoreductase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

(1) a pyranose + acceptor [math]\displaystyle{ \rightleftharpoons }[/math] a pyranos-2-ulose (or a pyranos-3-ulose or a pyranos-2,3-diulose) + reduced acceptor
(2) a pyranoside + acceptor [math]\displaystyle{ \rightleftharpoons }[/math] a pyranosid-3-ulose (or a pyranosid-3,4-diulose) + reduced acceptor

This enzyme requires FAD. A number of aldoses and ketoses in pyranose form, as well as glycosides, gluco-oligosaccharides, sucrose and lactose can act as a donor.

References

  1. "Pyranose 2-dehydrogenase, a novel sugar oxidoreductase from the basidiomycete fungus Agaricus bisporus". Archives of Microbiology 167 (2/3): 119–25. March 1997. doi:10.1007/s002030050424. PMID 9042751. 
  2. "C-2 and C-3 oxidation of D-Glc, and C-2 oxidation of D-Gal by pyranose dehydrogenase from Agaricus bisporus". Carbohydr. Res. 310: 151–156. 1998. doi:10.1016/s0008-6215(98)00151-7. 
  3. "Double oxidation of D-xylose to D-glycero -pentos-2,3-diulose (2,3-diketo-D-xylose) by pyranose dehydrogenase from the mushroom Agaricus bisporus". Carbohydrate Research 329 (1): 219–25. October 2000. doi:10.1016/s0008-6215(00)00167-1. PMID 11086703. 
  4. "Screening of basidiomycete fungi for the quinone-dependent sugar C-2/C-3 oxidoreductase, pyranose dehydrogenase, and properties of the enzyme from Macrolepiota rhacodes". Archives of Microbiology 176 (3): 178–86. September 2001. doi:10.1007/s002030100308. PMID 11511865. 
  5. "C-3 oxidation of non-reducing sugars by a fungal pyranose dehydrogenase: spectral characterization". J. Mol. Catal., B Enzym. 17: 91–100. 2002. doi:10.1016/s1381-1177(02)00014-0. 

External links