Biology:Sarsasapogenin 3β-glucosyltransferase
sarsasapogenin 3-β-glucosyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.4.1.193 | ||||||||
CAS number | 117698-14-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a sarsasapogenin 3β-glucosyltransferase (EC 2.4.1.193) is an enzyme that catalyzes the chemical reaction
- UDP-glucose + sarsasapogenin ⇌ UDP + sarsasapogenin 3-O-β-D-glucoside
Thus, the two substrates of this enzyme are UDP-glucose and sarsasapogenin [(3β,5β,25S)-spirostan-3-ol], whereas its two products are UDP and sarsasapogenin 3-O-β-D-glucoside.[1]
The enzyme was first isolated from the root of the common asparagus (Asparagus officinalis).[1] It is specific for substrate sterols with the uncommon 5β-configuration (sarsasapogenin and smilagenin), that is with a cis-linkage between the A and B rings of the steroid nucleus.[1]
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:(3β,5β,25S)-spirostan-3-ol 3-O-β-D-glucosyltransferase. This enzyme is also called uridine diphosphoglucose-sarsasapogenin glucosyltransferase.
References
- ↑ 1.0 1.1 1.2 "The occurrence of UDPG-dependent glucosyltransferase specific for sarsasapogenin in Asparagus officinalis", Phytochemistry 27 (9): 2743–47, 1988, doi:10.1016/0031-9422(88)80654-X
Original source: https://en.wikipedia.org/wiki/Sarsasapogenin 3β-glucosyltransferase.
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