Biology:Sulcatone reductase

From HandWiki
sulcatone reductase
Identifiers
EC number1.1.1.260
CAS number196522-54-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a sulcatone reductase (EC 1.1.1.260) is an enzyme that catalyzes the chemical reaction

sulcatol + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] sulcatone + NADH + H+

Thus, the two substrates of this enzyme are sulcatol and NAD+, whereas its 3 products are sulcatone, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is sulcatol:NAD+ oxidoreductase.

References

  • "Use of biological systems for the preparation of chiral molecules 3. An application in pheromone synthesis: Preparation of sulcatol enantiomers". J. Org. Chem. 52 (2): 256–260. 1987. doi:10.1021/jo00378a017. 
  • "Enantioselectivity of sulcatone reduction by some anaerobic bacteria". Enzyme and Microbial Technology 21 (2): 143–147. 1997. doi:10.1016/S0141-0229(96)00264-5. 
  • "Selection in chemostat culture of a mutant strain of Clostridium tryobutyricum improved in its reduction of ketones". J. Appl. Microbiol. Biotechnol. 35: 317–322. 1991.