Biology:TRNA-guanine15 transglycosylase
From HandWiki
Short description: Class of enzymes
| TRNA-guanine15 transglycosylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.2.48 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
TRNA-guanine15 transglycosylase (EC 2.4.2.48, tRNA transglycosylase, transfer ribonucleate glycosyltransferase, tRNA guanine15 transglycosidase, TGT, transfer ribonucleic acid guanine15 transglycosylase) is an enzyme with systematic name tRNA-guanine15:7-cyano-7-carbaguanine tRNA-D-ribosyltransferase.[1] This enzyme catalyses the following chemical reaction
- guanine15 in tRNA + 7-cyano-7-carbaguanine [math]\displaystyle{ \rightleftharpoons }[/math] 7-cyano-7-carbaguanine15 in tRNA + guanine
Archaeal tRNAs contain the modified nucleoside archaeosine at position 15.
References
- ↑ "Hypermodification of tRNA in Thermophilic archaea. Cloning, overexpression, and characterization of tRNA-guanine transglycosylase from Methanococcus jannaschii". The Journal of Biological Chemistry 275 (37): 28731–8. September 2000. doi:10.1074/jbc.M002174200. PMID 10862614.
External links
- TRNA-guanine15+transglycosylase at the US National Library of Medicine Medical Subject Headings (MeSH)
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