Chemistry:Birch bark

From HandWiki
Short description: Tree bark
A Russian birch bark letter from the 14th century
Birchbark shoes

Birch bark or birchbark is the bark of several Eurasian and North American birch trees of the genus Betula.

The strong and water-resistant cardboard-like bark can be easily cut, bent, and sewn, which has made it a valuable building, crafting, and writing material, since pre-historic times. Today, birch bark remains a popular type of wood for various handicrafts and arts.

Birch bark also contains substances of medicinal and chemical interest. Some of those products (such as betulin) also have fungicidal properties that help preserve bark artifacts, as well as food preserved in bark containers.

Collection and storage

Birchbark box with lid and bottom of birch wood

Removing birch bark from live trees is harmful to tree health and should be avoided. Instead, it can be removed fairly easily from the trunk or branches of dead wood, by cutting a slit lengthwise through the bark and pulling or prying it away from the wood. The best time for collection is spring or early summer, as the bark is of better quality and most easily removed.

Removing the outer (light) layer of bark from the trunk of a living tree may not kill it, but probably weakens it and makes it more prone to infections. Removal of the inner (dark) layer, the phloem, kills the tree by preventing the flow of sap to the roots.

To prevent it from rolling up during storage, the bark should be spread open and kept pressed flat.

Working

Birch bark can be cut with a sharp knife, and worked like cardboard. For sharp bending, the fold should be scored (scratched) first with a blunt stylus.

Fresh bark can be worked as is; bark that has dried up (before or after collection) should be softened by steaming, by soaking in warm water, or over a fire.

Uses

A birch bark longhouse on Whitefish Island in Canada
Finnish fishing net weights made out of birch bark and stones
North American birchbark canoe
Birchbark knife handle

Birch bark was a valuable construction material in any part of the world where birch trees were available. Containers such as wrappings, bags, baskets, boxes, or quivers were made by most societies well before pottery was invented[citation needed]. Other uses include:

  • In various Asian countries (including Siberia) birch bark was used to make storage boxes, paper, tinder, canoes, roof coverings, tents, and waterproof covering for composite bows, such as the Mongol bow, the Chinese bow, Korean bow, Turkish bows, Assyrian bow, the Perso-Parthian bow. It is still being used. More than one variety of birch is used.
  • In North America, the native population used birch bark for canoes,[1] wigwams, scrolls, ritual art (birch bark biting), maps (including the oldest maps of North America[2]), torches,[3] fans, musical instruments, clothing, and more.
  • In Scandinavia and Finland, it was used as the substratum of sod roofs and birch-bark roofs, for making boxes, casks and buckets, fishing implements, and shoes (as used by the Egtved Girl) similar to bast shoes.
  • In Russia, many birch bark manuscripts have survived from the Middle Ages.
  • Birch bark knife handles are popular tools to be made currently.
  • In India, birch-bark, along with dried palm leaves, were the primary writing supports before the widespread advent of paper in the second millennium CE.[4] The oldest known Buddhist manuscripts (some of the Gandharan Buddhist Texts), from Afghanistan, were written on birch bark.[5]
  • Neanderthals used birch bark to make a tar adhesive through the process of dry or destructive distillation.[6][7]

Birch bark also makes an outstanding tinder, as the inner layers will stay dry even through heavy rainstorms.

Medical uses

Birch triterpenes
Clinical data
Trade namesFilsuvez
Other namesOleogel-S10
AHFS/Drugs.comFilsuvez
License data
Routes of
administration
Topical
ATC code
  • None
Legal status
Legal status
Identifiers
KEGG

Birch bark, sold under the brand name Filsuvez, is a medication that is used to treat epidermolysis bullosa.[9]

The most common side effects with Filsuvez include wound complications.[9] Other common side effects include skin reactions at the application site, wound infections, pruritus (itching), and hypersensitivity (allergic) reactions.[9]

Epidermolysis bullosa is an inherited disease of the skin that makes the skin very fragile and causes severe blistering and scarring.[9] Filsuvez is used in two types of epidermolysis bullosa, dystrophic epidermolysis bullosa and junctional epidermolysis bullosa, to treat partial-thickness skin wounds.[9] These are wounds where the upper layers of the skin have been damaged.[9]

Filsuvez is indicated for the treatment of partial thickness wounds associated with dystrophic and junctional epidermolysis bullosa in people aged six months of age and older.[9] The US Food and Drug Administration (FDA) considers it to be a first-in-class medication.[10]

Legal status

In April 2022, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion, recommending the granting of a marketing authorization for the medicinal product Filsuvez, intended for the treatment of epidermolysis bullosa.[11] The applicant for this medicinal product is Amryt Pharmaceuticals DAC.[11] Filsuvez will be available as a gel for cutaneous use.[11] The active substance of Filsuvez is birch bark extract (as dry extract, refined) from Betula pendula Roth/Betula pubescens Ehrh. (equivalent to 0.5‑1.0 g birch bark), including 84‑95 mg triterpenes calculated as the sum of betulin, betulinic acid, erythrodiol, lupeol and oleanolic acid.[11] It is thought to work by modulating inflammatory mediators and stimulating keratinocyte differentiation and migration, thereby promoting wound healing and closure.[11] Filsuvez was approved for medical use in the European Union in June 2022,[9][12] and in the United States in December 2023.[13][14]

See also

References

  1. Vennum T, Weber C, Nyholm E (1999). Earl's Canoe: A Traditional Ojibwe Craft. Smithsonian Center for Folklife Programs and Cultural Studies. Archived from the original on 4 January 2013. Retrieved 3 December 2012.
  2. Historical Atlas of Canada: Canada's History Illustrated with Original Maps.. Vancouver: Douglas & McIntyre Ltd. 2002. p. 152. 
  3. Deep Cave Rock Art in the Upper Mississippi Valley. St. Paul: Prairie Smoke Press. 2003. pp. 54–55. ISBN 0-9704482-3-6. 
  4. The art of the book in India. British Library. Reference Division.. London: British Library. 1982. ISBN 0904654788. OCLC 8653520. 
  5. (in en) Ancient Buddhist scrolls from Gandhāra: the British Library Kharoṣṭhī fragments. London: The British Library. 1999. ISBN 0712346112. OCLC 263439456. 
  6. "Experimental methods for the Palaeolithic dry distillation of birch bark: implications for the origin and development of Neandertal adhesive technology" (in En). Scientific Reports 7 (1): 8033. August 2017. doi:10.1038/s41598-017-08106-7. PMID 28860591. Bibcode2017NatSR...7.8033K. 
  7. "Birch tar production does not prove Neanderthal behavioral complexity". Proceedings of the National Academy of Sciences of the United States of America 116 (36): 17707–17711. September 2019. doi:10.1073/pnas.1911137116. PMID 31427508. Bibcode2019PNAS..11617707S. 
  8. "Archived copy". https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/215064s000lbl.pdf. 
  9. 9.0 9.1 9.2 9.3 9.4 9.5 9.6 9.7 9.8 "Filsuvez EPAR". 13 April 2022. https://www.ema.europa.eu/en/medicines/human/EPAR/filsuvez.  Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
  10. (PDF) New Drug Therapy Approvals 2023 (Report). January 2024. https://www.fda.gov/media/175253/download. Retrieved 9 January 2024. 
  11. 11.0 11.1 11.2 11.3 11.4 "Filsuvez: Pending EC decision". 22 April 2022. https://www.ema.europa.eu/en/medicines/human/summaries-opinion/filsuvez.  Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
  12. "Filsuvez Product information". https://ec.europa.eu/health/documents/community-register/html/h1652.htm. 
  13. "Chiesi Global Rare Diseases Receives FDA Approval for Filsuvez (birch triterpenes) topical gel for the Treatment of Epidermolysis Bullosa". Chiesi Global Rare Diseases (Press release). 19 December 2023. Archived from the original on 22 December 2023. Retrieved 22 December 2023.
  14. "Novel Drug Approvals for 2023". 19 December 2023. https://www.fda.gov/drugs/new-drugs-fda-cders-new-molecular-entities-and-new-therapeutic-biological-products/novel-drug-approvals-2023. 

Further reading

Winter bark etching on canoe
  • The Survival of the Bark Canoe. New York: Farrar, Straus and Giroux. 1975. 
  • Bark Canoes and Skin Boats of North America. Skyhorse Publishing, Inc.. 2014. 
  • Bark Canoes: The Art and Obsession of Tappan Adney. Firefly Books Ltd.. 2004. 
  • The Travel Journals of Tappan Adney, 1887-1890. Estate of Tappan Adney. 2010. 
  • Ojibwe Birch Bark Canoes: Anishinaabe Wigwassi-Jiimaan. Beaver Bark Canoes. 2012. 

External links