Chemistry:Flupropadine
From HandWiki
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| Preferred IUPAC name
1-{3-[3,5-Bis(trifluoromethyl)phenyl]prop-2-yn-1-yl}-4-tert-butylpiperidine | |
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3D model (JSmol)
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| Properties | |
| C20H23F6N | |
| Molar mass | 391.401 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Flupropadine is a rodenticide.[1][2] Originally made by May and Baker[3] and tested on farms in the United Kingdom it was withdrawn from use by 1994.[4] Flupropadine has a delayed action, and so rodents can have multiple feeds from the bait before being killed.[5]
The molecule has two rings, one is a m-hexafluoroxylene, and the other is piperidine. Flupropadine is made from 3,5-bis(trifluoromethyl)iodobenzene, propargyl alcohol, and 4-tert-butylpiperidine.[6]
References
- ↑ Buckle, A. P (1985). "Field trials of a new sub-acute rodenticide flupropadine, against wild Norway rats (Rattus norvegicus)". The Journal of Hygiene 95 (2): 505–12. doi:10.1017/s0022172400062926. PMID 3840823.
- ↑ Rowe, F. P; Bradfield, A; Swinney, T (1985). "Pen and field trials of flupropadine against the house mouse (Mus musculus L.)". The Journal of Hygiene 95 (2): 513–8. doi:10.1017/s0022172400062938. PMID 4067302.
- ↑ Missio, Andrea (14 June 2006). "Hexafluoroxylenes: Fluorine Chemistry and Beyond". p. 7. http://www.rscspecialitychemicals.org.uk/docs/rsc-symposium/Hexafluoroxylenes-Fluorine-Chemistry-and-Beyond_Andrea-Missio_-RSC-Symposium-2006.pdf.
- ↑ Berny, Philipe (May 2003). "STATE-OF-THE-ART REPORT ON THE USE OF ANTICOAGULANT RODENTICIDES IN THE EU AND BEYOND". Communication and Information Resource Centre for Administrations, Businesses and Citizens. https://circabc.europa.eu/sd/a/791ca8b3-ce9e-4e73-a7ca-b3bee967cd3f/CA-May13-Doc.10.2%20-%20draft_report_bibliographic_review.docx. Retrieved 15 May 2018.
- ↑ Buckle, Alan P.; Smith, Robert H. (2015) (in en). Rodent Pests and Their Control, 2nd Edition. CABI. p. 116. ISBN 9781845938178. https://books.google.com/books?id=fNwcCgAAQBAJ&pg=PR116.
- ↑ Unger, Thomas A. (1996) (in en). Pesticide Synthesis Handbook. William Andrew. pp. 499–500. ISBN 9780815518532. https://books.google.com/books?id=-9cHDi8OOO4C&pg=PA499.
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