Chemistry:Oryzalin
From HandWiki
Oryzalin is an herbicide of the dinitroaniline class. It acts through the disruption (depolymerization) of microtubules, thus blocking anisotropic growth of plant cells.[1] It can also be used to induce polyploidy in plants as an alternative to colchicine.[2]
Roughly 250,000 pounds (110 t) was used in the US in 2019, down from about 750,000 pounds (340 t) in 2010, and 1,000,000 pounds (450 t) in 1995 (by USGS estimates).[3]
Research
Oryzalin has been studied for its potential use as an antiparasitic agent, particularly against Leishmania.[4][5]
References
- ↑ Plant Physiology (5th ed.). Sinauer Associates. 2010. pp. 433–434. ISBN 978-0-87893-866-7.
- ↑ "Chromosome doubling effects of selected antimitotic agents in Brassica napus microspore culture". Czech Journal of Genetics and Plant Breeding 44 (1): 30–36. January 2008. doi:10.17221/1328-CJGPB. http://www.agriculturejournals.cz/publicFiles/01063.pdf.
- ↑ "Pesticide Use Maps - Oryzalin". USGS. https://water.usgs.gov/nawqa/pnsp/usage/maps/show_map.php?year=2019&map=ORYZALIN&hilo=L&disp=Oryzalin.
- ↑ Chan, Marion Man-Ying; Triemer, Richard E.; Fong, Dunne (1991). "Effect of the anti-microtubule drug oryzalin on growth and differentiation of the parasitic protozoan Leishmania mexicana". Differentiation 46 (1): 15–21. doi:10.1111/j.1432-0436.1991.tb00861.x. PMID 2044859.
- ↑ Lopes, Rui M.; Corvo, M. Luísa; Eleutério, Carla V.; Carvalheiro, Manuela C.; Scoulica, Effie; Cruz, M. Eugénia M. (2012). "Formulation of oryzalin (ORZ) liposomes: In vitro studies and in vivo fate". European Journal of Pharmaceutics and Biopharmaceutics 82 (2): 281–290. doi:10.1016/j.ejpb.2012.06.013. PMID 22771930.
External links
- Oryzalin in the Pesticide Properties DataBase (PPDB)
 |  |
