Chemistry:Succinylsulfathiazole
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| Formula | C13H13N3O5S2 |
| Molar mass | 355.38 g·mol−1 |
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Succinylsulfathiazole (also known as sulfasuxidine) is a sulfonamide. It is also spelled as succinylsulphathiazole. It is a white or yellow-white crystalline powder. It dissolves in aqueous solutions of alkali hydroxides and carbonates but is very slightly soluble in water.
It is classified as ultra long acting drug. About 95% of the drug remains in the intestine and only 5% is hydrolyzed, slowly, to Sulfathiazole and is absorbed.
The drug is used for its antibacterial activity in the GIT. The dose is 10g - 20g daily in divided doses.
The Succinyl group is attached to form a Prodrug for Controlled release of drug Sulphathiazole.
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