Medicine:Table of medication secreted in kidney
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This is a table of medications that are secreted in the kidney. Acid medication are, because of pH partition, secreted to a higher extent when urine is basic. In the same way, basic medications are secreted to a higher extent when urine is acidic.
| Medication | Location | Acid or base[1] | anion or cation[2] | Percentage excreted[3] |
|---|---|---|---|---|
| para-aminohippurate | proximal tubule[4] | Acid | anion | |
| furosemide | proximal tubule[4] | Acid | anion | 100-75 |
| glucuronic acid-conjugates | proximal tubule[4] | Acid | ||
| glycine conjugates | proximal tubule[4] | Acid | ||
| indometacin | proximal tubule[4] | Acid | anion | |
| methotrexate | proximal tubule[4] | Acid | 100-75 | |
| penicillin | proximal tubule[4] | Acid | anion | 75-50 (benzylpenicillin) |
| probenecid | proximal tubule[4] | Acid | anion | |
| sulphate conjugates | proximal tubule[4] | Acid | ||
| thiazide diuretics | proximal tubule[4] | Acid | ||
| uric acid | proximal tubule[4] | Acid | ||
| amiloride | proximal tubule[4] | Base | cation | |
| dopamine | proximal tubule[4] | Base | ||
| histamine | proximal tubule[4] | Base | ||
| mepacrine | proximal tubule[4] | Base | ||
| morphine | proximal tubule[4] | Base | cation | |
| pethidine | proximal tubule[4] | Base | ||
| quaternary ammonium compounds | proximal tubule[4] | Base | ||
| quinine | proximal tubule[4] | Base | cation | |
| 5-hydroxytryptamine (serotonin) | proximal tubule[4] | Base | ||
| triamterene | proximal tubule[4] | Base | ||
| gentamicin | 100-75 | |||
| atenolol | 100-75 | |||
| digoxin | 100-75 | |||
| cimetidine | cation | 75-50 | ||
| tetracycline | 75-50 (oxytetracycline) | |||
| neostigmine | 75-50 | |||
| propantheline | ~50 | |||
| tubocurarine | ~50 | |||
| acetazolamide | proximal tubule[5] | anion | ||
| chlorothiazide | proximal tubule[5] | anion | ||
| saccharin | proximal tubule[5] | anion | ||
| salicylate | proximal tubule[5] | anion | ||
| atropine | proximal tubule[5] | cation | ||
| NMN | proximal tubule[5] | cation | ||
| paraquat | proximal tubule[5] | cation | ||
| procainamide | proximal tubule[5] | cation | ||
| tetraethylammonium | proximal tubule[5] | cation | ||
| chlorpromazine | proximal tubule[5] | cation |
References
- ↑ Unless else specified in table boxes, then ref is Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4. Page 112
- ↑ Unless else specified in table boxes, then ref is Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approach. Elsevier/Saunders. ISBN 1-4160-2328-3. Page 802
- ↑ Unless else specified in table boxes, then ref is Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4. Page 113
- ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 4.13 4.14 4.15 4.16 4.17 4.18 4.19 4.20 Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4. Page 112
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 5.8 5.9 Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approach. Elsevier/Saunders. ISBN 1-4160-2328-3. Page 802
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