Chemistry:Tilisolol

Tilisolol
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name (RS)-4-[3-(tert-butylamino)-2-hydroxypropoxy]-2-methylisoquinolin-1-one;
CAS Number	85136-71-6 ; 62774-96-3 (hydrochloride);
PubChem CID	5474;
ChemSpider	5275;
UNII	QUF41MF56G;
KEGG	D08598 ;
Chemical and physical data
Formula	C17H24N2O3
Molar mass	304.390 g·mol−1
3D model (JSmol)	Interactive image;
Chirality	Racemic mixture
	SMILES CC(C)(C)NCC(COC1=CN(C(=O)C2=CC=CC=C21)C)O;
	InChI InChI=1S/C17H24N2O3/c1-17(2,3)18-9-12(20)11-22-15-10-19(4)16(21)14-8-6-5-7-13(14)15/h5-8,10,12,18,20H,9,11H2,1-4H3; Key:TWVUMMQUXMYOOH-UHFFFAOYSA-N;
	(verify)

Short description: Chemical compound

Tilisolol (INN, trade name Selecal) is a beta blocker.^[1]

References

↑ "Vasodilating effect of the new beta-blocker tilisolol hydrochloride in humans". Arzneimittel-Forschung 38 (9): 1342–4. September 1988. PMID 2906248.

0.00

(0 votes)

Original source: https://en.wikipedia.org/wiki/Tilisolol. Read more

v t e Beta blockers (C07)
β, non-selective	Alprenolol Bopindolol Bupranolol Carteolol Cloranolol Mepindolol Nadolol Oxprenolol Penbutolol Pindolol/Iodopindolol Propranolol Sotalol Tertatolol Timolol
β₁-selective	Acebutolol Atenolol Betaxolol Bevantolol Bisoprolol Celiprolol Epanolol Esmolol Landiolol Metoprolol Nebivolol Practolol S-Atenolol Talinolol
β₂-selective	Butaxamine
α₁- + β-selective	Arotinolol Carvedilol Labetalol
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name (RS)-4-[3-(tert-butylamino)-2-hydroxypropoxy]-2-methylisoquinolin-1-one
CAS Number	85136-71-6^Y 62774-96-3 (hydrochloride)
PubChem CID	5474
ChemSpider	5275
UNII	QUF41MF56G
KEGG	D08598^Y
Chemical and physical data
Formula	C₁₇H₂₄N₂O₃
Molar mass	304.390 g·mol⁻¹
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
SMILES CC(C)(C)NCC(COC1=CN(C(=O)C2=CC=CC=C21)C)O
InChI InChI=1S/C17H24N2O3/c1-17(2,3)18-9-12(20)11-22-15-10-19(4)16(21)14-8-6-5-7-13(14)15/h5-8,10,12,18,20H,9,11H2,1-4H3 Key:TWVUMMQUXMYOOH-UHFFFAOYSA-N
(verify)