Biology:PRSS22
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Brain-specific serine protease 4 (BSSP-4), also known as serine protease 22 or tryptase epsilon, is an enzyme that in humans is encoded by the PRSS22 gene.[1][2][3]
This gene encodes a member of the trypsin family of serine proteases. The enzyme is expressed in the airways in a developmentally regulated manner. The gene is part of a cluster of serine protease genes on chromosome 16.[1]
See also
References
- ↑ 1.0 1.1 "Entrez Gene: protease". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64063.
- ↑ "Human tryptase epsilon (PRSS22), a new member of the chromosome 16p13.3 family of human serine proteases expressed in airway epithelial cells". J. Biol. Chem. 276 (52): 49169–82. December 2001. doi:10.1074/jbc.M108677200. PMID 11602603.
- ↑ "Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase epsilon/PRSS22". Blood 105 (10): 3893–901. May 2005. doi:10.1182/blood-2003-10-3501. PMID 15701722.
Further reading
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. 2003. doi:10.1101/gr.1293003. PMID 12975309.
- "The sequence and analysis of duplication-rich human chromosome 16.". Nature 432 (7020): 988–94. 2004. doi:10.1038/nature03187. PMID 15616553. Bibcode: 2004Natur.432..988M.
- "A novel serine protease highly expressed in the pancreas is expressed in various kinds of cancer cells.". FEBS J. 272 (19): 4911–23. 2005. doi:10.1111/j.1742-4658.2005.04901.x. PMID 16176265.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2002. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
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