Chemistry:Elapegademase
From HandWiki
| Clinical data | |
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| Trade names | Revcovi |
| Other names | elapegademase-lvlr |
| AHFS/Drugs.com | Monograph |
| License data | |
| Routes of administration | Intramuscular |
| ATC code | |
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Elapegademase, sold under the brand name Revcovi, is a medication for the treatment of the rare disease adenosine deaminase deficiency-SCID in children and adults.[1]
It is a recombinant enzyme[2] that is administered weekly by intramuscular injection.[3]
Elapegademase may interact with PEGylated drugs.[3]
Elapegademase-lvlr was approved by the U.S. Food and Drug Administration (FDA) in 2018.[4][5][6] Leadiant Biosciences was awarded a priority review voucher for its development under the pediatric rare diseases program.[7]
References
- ↑ "Elapegademase". Mosby's 2023 Nursing Drug Reference. Elsevier Health Sciences. 2022. p. 429. ISBN 978-0-323-93330-8. https://books.google.com/books?id=S2ZsEAAAQBAJ&dq=Elapegademase&pg=PA429.
- ↑ "Elapegademase: Drug Information". https://www.uptodate.com/contents/elapegademase-drug-information. Retrieved 28 March 2019.
- ↑ 3.0 3.1 "LexiComp: Elapegademase-lvlr". http://online.lexi.com/lco/action/doc/retrieve/docid/fc_atoz2/6712838?hl=832641. Retrieved 28 March 2019.
- ↑ "Drug Approval Package: Revcovi". 7 November 2018. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2018/761092Orig1s000TOC.cfm.
- ↑ "Elapegademase-lvlr Orphan Drug Designation and Approval". 24 December 1999. https://www.accessdata.fda.gov/scripts/opdlisting/oopd/detailedIndex.cfm?cfgridkey=467514.
- ↑ "Drug Trial Snapshot: Revcovi". 5 October 2018. http://www.fda.gov/drugs/drug-approvals-and-databases/drug-trial-snapshot-revcovi.
- ↑ "Elapegademase - Leadiant Biosciences". AdisInsight. Springer Nature Switzerland AG. https://adisinsight.springer.com/drugs/800034312. Retrieved 28 March 2019.
External links
- "Elapegademase". Drug Information Portal. U.S. National Library of Medicine. https://druginfo.nlm.nih.gov/drugportal/name/elapegademase.
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