Biology:Soluble quinoprotein glucose dehydrogenase
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Soluble quinoprotein glucose dehydrogenase | |||||||||
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Identifiers | |||||||||
EC number | 1.1.99.35 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Soluble quinoprotein glucose dehydrogenase (EC 1.1.99.35, soluble glucose dehydrogenase, sGDH, glucose dehydrogenase (PQQ-dependent)) is an enzyme with systematic name D-glucose:acceptor oxidoreductase.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- D-glucose + acceptor [math]\displaystyle{ \rightleftharpoons }[/math] D-glucono-1,5-lactone + reduced acceptor
This soluble periplasmic enzyme contains PQQ as prosthetic group, and is bound to a calcium ion. Electron acceptor is not known.
References
- ↑ "Crystalline quinoprotein glucose dehydrogenase from Acinetobacter calcoaceticus". Biochemistry 25: 6043–6048. 1986. doi:10.1021/bi00368a031.
- ↑ "Purification and characterization of quinoprotein glucose dehydrogenase from Acinetobacter calcoaceticus L.M.D. 79.41". The Biochemical Journal 239 (1): 163–7. October 1986. PMID 3800975.
- ↑ "Cloning of the gene encoding quinoprotein glucose dehydrogenase from Acinetobacter calcoaceticus: evidence for the presence of a second enzyme". Journal of Bacteriology 170 (5): 2121–5. May 1988. PMID 2834325.
- ↑ "Quinoprotein D-glucose dehydrogenase of the Acinetobacter calcoaceticus respiratory chain: membrane-bound and soluble forms are different molecular species". Biochemistry 28 (15): 6276–80. July 1989. doi:10.1021/bi00441a020. PMID 2551369.
- ↑ "Structural requirements of pyrroloquinoline quinone dependent enzymatic reactions". Protein Science 9 (7): 1265–73. July 2000. doi:10.1110/ps.9.7.1265. PMID 10933491.
- ↑ Matsushita, K.; Toyama, H.; Ameyama, M.; Adachi, O.; Dewanti, A.; Duine, J.A. (1995). "Soluble and membrane-bound quinoprotein D-glucose dehydrogenases of the Acinetobacter calcoaceticus : the binding process of PQQ to the apoenzymes". Biosci. Biotechnol. Biochem. 59: 1548–1555. doi:10.1271/bbb.59.1548.
External links
- Soluble+quinoprotein+glucose+dehydrogenase at the US National Library of Medicine Medical Subject Headings (MeSH)
Original source: https://en.wikipedia.org/wiki/Soluble quinoprotein glucose dehydrogenase.
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