Biology:L-lysine-lactamase
From HandWiki
L-lysine-lactamase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC number | 3.5.2.11 | ||||||||
CAS number | 52652-61-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
|
In enzymology, a L-lysine-lactamase (EC 3.5.2.11) is an enzyme that catalyzes the chemical reaction
- L-lysine 1,6-lactam + H2O [math]\displaystyle{ \rightleftharpoons }[/math] L-lysine
Thus, the two substrates of this enzyme are L-lysine 1,6-lactam and H2O, whereas its product is L-lysine.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is L-lysine-1,6-lactam lactamhydrolase. Other names in common use include L-alpha-aminocaprolactam hydrolase, and L-lysinamidase.
References
- "Purification and properties of a novel enzyme, L-alpha-amino-epsilon-caprolactamase from Cryptococcus laurentii". FEBS Lett. 89 (2): 298–300. 1978. doi:10.1016/0014-5793(78)80240-3. PMID 26602.
- Shvyadas, VK; Galaev, IYu; Kozlova, EV (1984). "Preparation and characterization of L-alpha-aminocaprolactam hydrolase from cells of Cryptococcus laurentii". Biochemistry (Moscow) 49: 1268–1273.
![]() | Original source: https://en.wikipedia.org/wiki/L-lysine-lactamase.
Read more |