Biology:dCMP deaminase
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
| dCMP deaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Deoxycytidylate deaminase hexamer, Cyanophage s-tim5 | |||||||||
| Identifiers | |||||||||
| EC number | 3.5.4.12 | ||||||||
| CAS number | 9026-92-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
| dCMP deaminase | |
|---|---|
| Identifiers | |
| Symbol | DCTD |
| NCBI gene | 1635 |
| HGNC | 2710 |
| OMIM | 607638 |
| RefSeq | NM_001921 |
| UniProt | P32321 |
| Other data | |
| EC number | 3.5.4.12 |
| Locus | Chr. 4 q35.1 |
dCMP deaminase (EC 3.5.4.12) is an enzyme which in humans is encoded by the gene DCTD. The name refers to its enzymatic activity which converts deoxycytidylic acid to deoxyuridylic acid. Alternate names for the enzyme include deoxycytidylate deaminase, deoxy-CMP-deaminase, deoxycytidylate aminohydrolase, deoxycytidine monophosphate deaminase, and deoxycytidine-5'-phosphate deaminase, deoxycytidine-5'-monophosphate aminohydrolase.[1][2][3]
References
- ↑ "The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. I. The enzymatic deamination of deoxycytidine 5'-phosphate and of 5-methyldeoxycytidine 5-methyldeoxycytidine 5'-phosphate". The Journal of Biological Chemistry 235 (3): 706–13. March 1960. doi:10.1016/S0021-9258(19)67927-5. PMID 14442222.
- ↑ "The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. II. Purification and properties of a 6-aminopyrimidine deoxyribonucleoside 5'-phosphate deaminase from unfertilized eggs of sea urchine". The Journal of Biological Chemistry 235 (12): 3556–61. December 1960. doi:10.1016/S0021-9258(18)64507-7. PMID 13747062.
- ↑ "On the regulation of a bacterial deoxycytidylate deaminase". The Journal of Biological Chemistry 246 (24): 7755–8. December 1971. doi:10.1016/S0021-9258(19)45839-0. PMID 5002683.
External links
- dCMP+deaminase at the US National Library of Medicine Medical Subject Headings (MeSH)
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