Biology:DNA alpha-glucosyltransferase
DNA alpha-glucosyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.4.1.26 | ||||||||
CAS number | 9030-13-1 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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In enzymology, a DNA alpha-glucosyltransferase (EC 2.4.1.26) is an enzyme that catalyzes the chemical reaction in which an alpha-D-glucosyl residue is transferred from UDP-glucose to a hydroxymethylcytosine residue in DNA.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:DNA alpha-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-deoxyribonucleate, alpha-glucosyltransferase, UDP-glucose-DNA alpha-glucosyltransferase, uridine diphosphoglucose-deoxyribonucleate, alpha-glucosyltransferase, T2-HMC-alpha-glucosyl transferase, T4-HMC-alpha-glucosyl transferase, and T6-HMC-alpha-glucosyl transferase.
Structural studies
As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes 1XV5, 1Y6F, 1Y6G, 1Y8Z, and 1YA6.
References
- "Glucosylation of deoxyribonucleic acid by enzymes from bacteriophage-infected Escherichia coli". J. Biol. Chem. 236: 1487–1493. 1961. PMID 13753193.
![]() | Original source: https://en.wikipedia.org/wiki/DNA alpha-glucosyltransferase.
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