Biology:Chenodeoxycholoyltaurine hydrolase
From HandWiki
| chenodeoxycholoyltaurine hydrolase | |||||||||
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| Identifiers | |||||||||
| EC number | 3.5.1.74 | ||||||||
| CAS number | 125752-75-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a chenodeoxycholoyltaurine hydrolase (EC 3.5.1.74) is an enzyme that catalyzes the chemical reaction
- chenodeoxycholoyltaurine + H2O [math]\displaystyle{ \rightleftharpoons }[/math] chenodeoxycholate + taurine
Thus, the two substrates of this enzyme are chenodeoxycholoyltaurine and H2O, whereas its two products are chenodeoxycholate and taurine.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is chenodeoxycholoyltaurine amidohydrolase. This enzyme participates in bile acid biosynthesis.
References
- "Purification and characterization of a new hydrolase for conjugated bile acids, chenodeoxycholyltaurine hydrolase, from Bacteroides vulgatus". J. Biochem. (Tokyo) 106 (6): 1049–53. December 1989. PMID 2628421.
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