Biology:Histolysain
From HandWiki
| Histolysin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.4.22.35 | ||||||||
| CAS number | 92228-52-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Histolysin (EC 3.4.22.35, histolysin, Entamoeba histolytica cysteine proteinase, amebapain, Entamoeba histolytica cysteine protease, Entamoeba histolytica neutral thiol proteinase) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
- Hydrolysis of proteins, including basement membrane collagen and azocasein. Preferential cleavage: Arg-Arg- in small molecule substrates including Z-Arg-Arg-!NHMec
This enzyme is present in the protozoan, Entamoeba histolytica.
References
- ↑ "Entamoeba histolytica: purification of cathepsin B". Experimental Parasitology 59 (3): 328–36. June 1985. doi:10.1016/0014-4894(85)90088-8. PMID 2860002.
- ↑ "Affinity purification and biochemical characterization of histolysin, the major cysteine proteinase of Entamoeba histolytica". The Biochemical Journal 250 (3): 903–9. March 1988. doi:10.1042/bj2500903. PMID 2898937.
External links
- Histolysain at the US National Library of Medicine Medical Subject Headings (MeSH)
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