Biology:N,N-dimethylformamidase
From HandWiki
Short description: Class of enzymes
| N,N-dimethylformamidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.5.1.56 | ||||||||
| CAS number | 104645-73-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a N,N-dimethylformamidase (EC 3.5.1.56) is an enzyme that catalyzes the chemical reaction
- N,N-dimethylformamide + H2O [math]\displaystyle{ \rightleftharpoons }[/math] dimethylamine + formate
Thus, the two substrates of this enzyme are N,N-dimethylformamide and H2O, whereas its two products are dimethylamine and formate.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N,N-dimethylformamide amidohydrolase. Other names in common use include dimethylformamidase, and DMFase. This enzyme participates in glyoxylate and dicarboxylate metabolism. It employs one cofactor, iron.
References
- "Purification and characterization of N,N-dimethylformamidase from Pseudomonas DMF 3/3". Eur. J. Biochem. 158 (3): 469–75. 1986. doi:10.1111/j.1432-1033.1986.tb09778.x. PMID 3732281.
 |  |
