Biology:Oviductin
From HandWiki
| Oviductin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.4.21.120 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Oviductin (EC 3.4.21.120, oviductal protease) is an enzyme found in the Japanese toad (Bufo japonicus) and in the African clawed frog (Xenopus laevis).[1][2][3] Ovulated coelomic egg cells are not fertilisable in these species until they pass through the oviduct, where Oviductin is located.[4] Oviductin catalyses the following chemical reaction in Xenopus laevis:
- Preferential cleavage at Gly-Ser-Arg373- of glycoprotein gp43 in the coelemic egg envelope to yield gp41.
References
- ↑ "Oviductin. Purification and properties of the oviductal protease that processes the molecular weight 43,000 glycoprotein of the Xenopus laevis egg envelope". Biochemistry 31 (18): 4466–72. May 1992. doi:10.1021/bi00133a012. PMID 1581303.
- ↑ "Oviductin, the Xenopus laevis oviductal protease that processes egg envelope glycoprotein gp43, increases sperm binding to envelopes, and is translated as part of an unusual mosaic protein composed of two protease and several CUB domains". Biology of Reproduction 60 (4): 989–95. April 1999. doi:10.1095/biolreprod60.4.989. PMID 10084976.
- ↑ "Oviductin, the oviductal protease that mediates gamete interaction by affecting the vitelline coat in Bufo japonicus: its molecular cloning and analyses of expression and posttranslational activation". Developmental Biology 243 (1): 176–84. March 2002. doi:10.1006/dbio.2001.0558. PMID 11846486.
- ↑ Hiyoshi, Masateru; Takamune, Kazufumi; Mita, Koichi; Kubo, Hideo; Sugimoto, Yasusi; Katagiri, Chiaki (March 2002). "Oviductin, the Oviductal Protease That Mediates Gamete Interaction by Affecting the Vitelline Coat in Bufo japonicus: Its Molecular Cloning and Analyses of Expression and Posttranslational Activation" (in en). Developmental Biology 243 (1): 176–184. doi:10.1006/dbio.2001.0558. PMID 11846486.
External links
- Oviductin at the US National Library of Medicine Medical Subject Headings (MeSH)
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