Biology:4-acetamidobutyryl-CoA deacetylase
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Short description: Class of enzymes
4-acetamidobutyryl-CoA deacetylase | |||||||||
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Identifiers | |||||||||
EC number | 3.5.1.51 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a 4-acetamidobutyryl-CoA deacetylase (EC 3.5.1.51) is an enzyme that catalyzes the chemical reaction
- 4-acetamidobutanoyl-CoA + H2O [math]\displaystyle{ \rightleftharpoons }[/math] acetate + 4-aminobutanoyl-CoA
Thus, the two substrates of this enzyme are 4-acetamidobutanoyl-CoA and H2O, whereas its two products are acetate and 4-aminobutanoyl-CoA.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is 4-acetamidobutanoyl-CoA amidohydrolase. Other names in common use include aminobutyryl-CoA thiolesterase, and deacetylase-thiolesterase.
References
- "Metabolism of L-beta-lysine by a Pseudomonas. Purification and properties of a deacetylase-thiolesterase utilizing 4-acetamidobutyryl CoA and related compounds". J. Biol. Chem. 256 (14): 7642–51. 1981. PMID 6788773.
![]() | Original source: https://en.wikipedia.org/wiki/4-acetamidobutyryl-CoA deacetylase.
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