Biology:4-hydroxyquinoline 3-monooxygenase
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Short description: Class of enzymes
| 4-hydroxyquinoline 3-monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.14.13.62 | ||||||||
| CAS number | 144378-37-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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4-hydroxyquinoline 3-monooxygenase (EC 1.14.13.62) is an enzyme that catalyzes the chemical reaction
- REDIRECT Template:Chemical reaction
The four substrates of this enzyme are 4-quinolone, reduced nicotinamide adenine dinucleotide (NADH), oxygen, and a proton. Its products are 3-hydroxyquinolin-4(1H)-one, oxidised NAD+, and water.[1][2]
This enzyme is an oxidoreductase, acting on paired donors, with molecular oxygen as oxidant and incorporation of one of its atoms. The systematic name of this enzyme class is quinolin-4(1H)-one,NADH:oxygen oxidoreductase (3-oxygenating). This enzyme is also called quinolin-4(1H)-one 3-monooxygenase.
References
- ↑ Enzyme 1.14.13.62 at KEGG Pathway Database.
- ↑ "Microbial metabolism of quinoline and related compounds. XIII Purification and properties of 1H-4-oxoquinoline monooxygenase from Pseudomonas putida strain 33/1". Biol. Chem. Hoppe-Seyler 373 (5): 249–54. 1992. doi:10.1515/bchm3.1992.373.1.249. PMID 1627263.
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