Biology:Adrenal androgen-stimulating hormone

From HandWiki

Adrenal androgen stimulating hormone (AASH), also known as cortical androgen stimulating hormone (CASH), is a hypothetical hormone which has been proposed to stimulate the adrenal glands to produce adrenal androgens such as dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), and androstenedione (A4).[1][2] It is hypothesized to be involved in adrenarche and adrenopause.[1][2] The existence of this hormone is controversial and disputed and it has not been identified to date.[1] A number of other mechanisms and/or hormones may instead play the functional role of the so-called AASH.[1][2][3]

See also

  • Adrenocorticotrophic hormone (ACTH)

References

  1. ↑ 1.0 1.1 1.2 1.3 "The adrenal androgen-stimulating hormone does not exist". Lancet 2 (8192): 454–6. August 1980. doi:10.1016/s0140-6736(80)91889-9. PMID 6106101. 
  2. ↑ 2.0 2.1 2.2 "Intraadrenal mechanisms of DHEA regulation: a hypothesis for adrenopause". Exp Clin Endocrinol Diabetes 109 (2): 75–82. 2001. doi:10.1055/s-2001-14826. PMID 11341302. 
  3. ↑ "Control of adrenal androgen secretion". Endocrinol Metab Clin North Am 20 (2): 401–21. June 1991. doi:10.1016/S0889-8529(18)30275-5. PMID 1652437. 



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