Biology:Carnitinamidase

From HandWiki
carnitinamidase
Identifiers
EC number3.5.1.73
CAS number117444-04-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a carnitinamidase (EC 3.5.1.73) is an enzyme that catalyzes the chemical reaction

L-carnitinamide + H2O [math]\displaystyle{ \rightleftharpoons }[/math] L-carnitine + NH3

Thus, the two substrates of this enzyme are L-carnitinamide and H2O, whereas its two products are L-carnitine and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is L-carnitinamide amidohydrolase. Other names in common use include L-carnitinamidase, carnitine amidase, and L-carnitine amidase.[1]

References

  1. "Carnitinamidase". Enzyme Handbook. 16. Heidelberg: Springer, Berlin. 1998. pp. 609–612. doi:10.1007/978-3-642-58903-4_118. ISBN 978-3-642-58903-4. 

Further reading

  • Nakayama K, Honda H, Ogawa Y, Ozawa T, Ohta T, "Method for producing carnitine, L-carnitinamide hydrolase and method for producing same", US patent 4918012, issued 17 April 1990, assigned to Kyowa Hakko Kogyo Co Ltd.