Biology:Cucumisin

From HandWiki
Short description: Enzyme
Cucumisin
Identifiers
EC number3.4.21.25
CAS number82062-89-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Cucumisin (EC 3.4.21.25, euphorbain, solanain, hurain, tabernamontanain) is an enzyme.[1][2][3][4][5][6][7] This enzyme catalyzes hydrolysis of a wide range of proteins. It has been identified as an allergen in humans.[8]

This enzyme is isolated from the sarcocarp of the musk melon (Cucumis melo).

References

  1. "Plant proteases. I. Activation-inhibition reactions". J. Biol. Chem. 135: 761–773. 1940. 
  2. "Hurain, a new plant protease from Hura crepitans". J. Biol. Chem. 149: 1–7. 1943. 
  3. "A new vegetable proteolytic enzyme of the papain class". Rev. Brasil Biol. 3: 149–157. 1943. 
  4. "Isolation and characterization of a proteinase from the sarcocarp of melon fruit". Journal of Biochemistry 78 (6): 1287–96. December 1975. PMID 5423. 
  5. "Amino acid sequence around the reactive serine of cucumisin from melon fruit". Journal of Biochemistry 95 (3): 825–9. March 1984. PMID 6427203. 
  6. "Two proteases from the latex of Elaeophorbia drupifera". Phytochemistry 24: 2843–2845. 1985. doi:10.1016/0031-9422(85)80011-x. 
  7. "Specificity of cucumisin in hydrolysis of peptide thiobenzyl esters". Agric. Biol. Chem. 50: 1075–1076. 1986. doi:10.1271/bbb1961.50.1075. 
  8. "Molecular Cloning and Expression of Cucumisin (Cuc m 1), a Subtilisin-like Protease of Cucumis melo in Escherichia coli". Allergology International 60 (1): 61–67. 2011. doi:10.2332/allergolint.10-OA-0195. 

External links