Biology:Degenerative disease

From HandWiki
Short description: Type of disease

Degenerative disease is the result of a continuous process based on degenerative cell changes, affecting tissues or organs, which will increasingly deteriorate over time.[1]

In neurodegenerative diseases, cells of the central nervous system stop working or die via neurodegeneration. An example of this is Alzheimer's disease.[2] The other two common groups of degenerative diseases are those that affect circulatory system (e.g. coronary artery disease) and neoplastic diseases (e.g. cancers).[1]

Many degenerative diseases exist and some are related to aging. Normal bodily wear or lifestyle choices (such as exercise or eating habits) may worsen degenerative diseases, but this depends on the disease.[1] Sometimes the main or partial cause behind such diseases is genetic.[3] Thus some are clearly hereditary like Huntington's disease.[4] Sometimes the cause is viruses, poisons or other chemicals. The cause may also be unknown.[3]

Some degenerative diseases can be cured. In those that can not, it may be possible to alleviate the symptoms.[1]

Examples


See also

References

  1. 1.0 1.1 1.2 1.3 1.4 "What is Degenerative Disease". https://www.docdoc.com.sg/info/condition/degenerative-disease/. 
  2. "neurodegenerative disorder". 2011-02-02. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/neurodegenerative-disorder. 
  3. 3.0 3.1 "Neurodegenerative Diseases". https://medlineplus.gov/degenerativenervediseases.html. 
  4. 4.0 4.1 Nopoulos, PC (2016). "Huntington disease: a single-gene degenerative disorder of the striatum". Dialogues in Clinical Neuroscience 18 (1): 91–98. doi:10.31887/DCNS.2016.18.1/pnopoulos. ISSN 1294-8322. PMID 27069383. 
  5. 5.0 5.1 5.2 5.3 Soto, C; Satani, N (2011). "The intricate mechanisms of neurodegeneration in prion diseases". Trends in Molecular Medicine 17 (1): 14–24. doi:10.1016/j.molmed.2010.09.001. ISSN 1471-4914. PMID 20889378. 
  6. Patzkó, Á; Shy, ME (2011). "Update on Charcot-Marie-Tooth Disease". Current Neurology and Neuroscience Reports 11 (1): 78–88. doi:10.1007/s11910-010-0158-7. ISSN 1528-4042. PMID 21080241. 
  7. Maroon, JC; Winkelman, R; Bost, J; Amos, A; Mathyssek, C; Miele, V (2015-02-11). "Chronic Traumatic Encephalopathy in Contact Sports: A Systematic Review of All Reported Pathological Cases". PLOS ONE 10 (2): e0117338. doi:10.1371/journal.pone.0117338. ISSN 1932-6203. PMID 25671598. Bibcode2015PLoSO..1017338M. 
  8. Fraser-Pitt, D; O’Neil, D (2015). "Cystic fibrosis – a multiorgan protein misfolding disease". Future Science OA 1 (2): FSO57. doi:10.4155/fso.15.57. ISSN 2056-5623. PMID 28031875. 
  9. "Cytochrome c oxidase deficiency". https://rarediseases.info.nih.gov/diseases/48/cytochrome-c-oxidase-deficiency. 
  10. "Ehlers-Danlos syndromes". https://rarediseases.info.nih.gov/diseases/6322/ehlers-danlos-syndromes. 
  11. Delatycki, M; Williamson, R; Forrest, S (2000). "Friedreich ataxia: an overview". Journal of Medical Genetics 37 (1): 1–8. doi:10.1136/jmg.37.1.1. ISSN 0022-2593. PMID 10633128. 
  12. Warren, JD; Rohrer, JD; Rossor, MN (2013-08-06). "Frontotemporal dementia". The BMJ 347: f4827. doi:10.1136/bmj.f4827. ISSN 0959-8138. PMID 23920254. 
  13. Barik, R (2016). "Degenerative aortic valve disease and coronary artery disease are either side of a coin". Indian Heart Journal 68 (3): 432. doi:10.1016/j.ihj.2015.09.010. ISSN 0019-4832. PMID 27316510. 
  14. Li, H; Zou, Y; Bao, X; Wang, H; Wang, J; Jin, H; Che, Y; Tang, X (2016). "Monozygotic twins with infantile neuroaxonal dystrophy: A case report and literature review". Experimental and Therapeutic Medicine 12 (5): 3387–3389. doi:10.3892/etm.2016.3761. ISSN 1792-0981. PMID 27882168. 
  15. Davidson, AE; Hayes, S; Hardcastle, AJ; Tuft, SJ (2014). "The pathogenesis of keratoconus". Eye 28 (2): 189–195. doi:10.1038/eye.2013.278. ISSN 0950-222X. PMID 24357835. 
  16. Wallang, BS; Das, S (2013). "Keratoglobus". Eye 27 (9): 1004–1012. doi:10.1038/eye.2013.130. ISSN 0950-222X. PMID 23807384. 
  17. van der Knaap, MS; Bugiani, M (2017). "Leukodystrophies: a proposed classification system based on pathological changes and pathogenetic mechanisms". Acta Neuropathologica 134 (3): 351–382. doi:10.1007/s00401-017-1739-1. ISSN 0001-6322. PMID 28638987. 
  18. Anand, A; Sharma, K; Chen, W; Sharma, NK (2014). "Using Current Data to Define New Approach in Age Related Macular Degeneration: Need to Accelerate Translational Research". Current Genomics 15 (4): 266–277. doi:10.2174/1389202915666140516204512. ISSN 1389-2029. PMID 25132797. 
  19. Gao, L; Luo, F; Hui, R; Zhou, X (2010). "Recent molecular biological progress in Marfan syndrome and Marfan-associated disorders" (in en). Ageing Research Reviews 9 (3): 363–368. doi:10.1016/j.arr.2009.09.001. ISSN 1568-1637. PMID 19772952. 
  20. "MELAS Syndrome". NORD (National Organization for Rare Disorders). https://rarediseases.org/rare-diseases/melas-syndrome/. 
  21. El-Hattab, AW; Scaglia, F (2013). "Mitochondrial DNA Depletion Syndromes: Review and Updates of Genetic Basis, Manifestations, and Therapeutic Options". Neurotherapeutics 10 (2): 186–198. doi:10.1007/s13311-013-0177-6. ISSN 1933-7213. PMID 23385875. 
  22. Hermena, Shady; Francis, Monica (2021-10-11). "Clinical Presentation, Imaging Features, and Management of Müller–Weiss Disease" (in en). Cureus 13 (10): e18659. doi:10.7759/cureus.18659. ISSN 2168-8184. PMID 34786245. 
  23. Fitzner, D; Simons, M (2010). "Chronic Progressive Multiple Sclerosis – Pathogenesis of Neurodegeneration and Therapeutic Strategies". Current Neuropharmacology 8 (3): 305–315. doi:10.2174/157015910792246218. ISSN 1570-159X. PMID 21358979. 
  24. Ubhi, K; Low, P; Masliah, E (2011). "Multiple System Atrophy: A Clinical and Neuropathological Perspective". Trends in Neurosciences 34 (11): 581–590. doi:10.1016/j.tins.2011.08.003. ISSN 0166-2236. PMID 21962754. 
  25. Shin, J; Tajrishi, MM; Ogura, Y; Kumar, A (2013). "Wasting Mechanisms in Muscular Dystrophy". The International Journal of Biochemistry & Cell Biology 45 (10): 2266–2279. doi:10.1016/j.biocel.2013.05.001. ISSN 1357-2725. PMID 23669245. 
  26. Mole, SE; Williams, Ruth E. (1993). "Neuronal Ceroid-Lipofuscinoses – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY". in Adam, Margaret P.; Ardinger, Holly H.; Pagon, Roberta A. et al.. Neuronal Ceroid-Lipofuscinoses. University of Washington, Seattle. https://www.ncbi.nlm.nih.gov/books/NBK1428/. Retrieved 2018-09-17. 
  27. Evans, WRH; Hendriksz, CJ (2017). "Niemann–Pick type C disease – the tip of the iceberg? A review of neuropsychiatric presentation, diagnosis and treatment". BJPsych Bulletin 41 (2): 109–114. doi:10.1192/pb.bp.116.054072. ISSN 2056-4694. PMID 28400970. 
  28. 28.0 28.1 Shen, Y; Zhang, Y; Shen, L (2013-04-15). "Postmenopausal women with osteoporosis and osteoarthritis show different microstructural characteristics of trabecular bone in proximal tibia using high-resolution magnetic resonance imaging at 3 tesla". BMC Musculoskeletal Disorders 14: 136. doi:10.1186/1471-2474-14-136. ISSN 1471-2474. PMID 23587336. 
  29. Bazan, IS; Fares, WH (2015-08-17). "Pulmonary hypertension: diagnostic and therapeutic challenges". Therapeutics and Clinical Risk Management 11: 1221–1233. doi:10.2147/TCRM.S74881. ISSN 1176-6336. PMID 26316767. 
  30. Owolabi, LF (2013). "Progressive Supranuclear Palsy Misdiagnosed as Parkinson's Disease: A Case Report and Review of Literature". Annals of Medical and Health Sciences Research 3 (Suppl1): S44–S47. doi:10.4103/2141-9248.121221. ISSN 2141-9248. PMID 24349849. 
  31. Hamel, C (2006-10-11). "Retinitis pigmentosa". Orphanet Journal of Rare Diseases 1: 40. doi:10.1186/1750-1172-1-40. ISSN 1750-1172. PMID 17032466. 
  32. Abdel-Ahad, P; El Chammai, M; Fneich, A; Issa, R; Kabbara, W; Richa, S (2016). "Les manifestations psychiatriques dans la polyarthrite rhumatoïde". L'Encéphale 42 (2): 172–176. doi:10.1016/j.encep.2015.12.008. ISSN 0013-7006. PMID 26850214. 
  33. 33.0 33.1 Walia, JP; Altaleb, N; Bello, A; Kruck, C; LaFave, MC; Varshney, GK; Burgess, SM; Chowdhury, B et al. (2015). "Long-Term Correction of Sandhoff Disease Following Intravenous Delivery of rAAV9 to Mouse Neonates". Molecular Therapy 23 (3): 414–422. doi:10.1038/mt.2014.240. ISSN 1525-0016. PMID 25515709. 
  34. Simone, C; Ramirez, A; Bucchia, M; Rinchetti, P; Rideout, H; Papadimitriou, D; Re, DB; Corti, S (2016). "Is Spinal Muscular Atrophy a disease of the motor neurons only: pathogenesis and therapeutic implications?". Cellular and Molecular Life Sciences 73 (5): 1003–1020. doi:10.1007/s00018-015-2106-9. ISSN 1420-682X. PMID 26681261. 
  35. Jafri, SK; Kumar, R; Ibrahim, SH (2018-06-26). "Subacute sclerosing panencephalitis – current perspectives". Pediatric Health, Medicine and Therapeutics 9: 67–71. doi:10.2147/PHMT.S126293. ISSN 1179-9927. PMID 29985487. 
  36. "Brain Disease Model of Drug & Alcohol Addiction | Hazelden Betty Ford". https://www.hazeldenbettyford.org/education/bcr/addiction-research/brain-disease-model-ru-316#:~:text=Patients%3A%20Addiction%20is%20a%20degenerative,be%20reversed%20through%20sustained%20abstinence.. 
  37. Korczyn, AD; Vakhapova, V; Grinberg, LT (2012-11-15). "Vascular dementia". Journal of the Neurological Sciences 322 (1–2): 2–10. doi:10.1016/j.jns.2012.03.027. ISSN 0022-510X. PMID 22575403.