Biology:Dehydrogluconate dehydrogenase
From HandWiki
| dehydrogluconate dehydrogenase | |||||||||
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| Identifiers | |||||||||
| EC number | 1.1.99.4 | ||||||||
| CAS number | 9028-82-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, dehydrogluconate dehydrogenase (EC 1.1.99.4) is an enzyme that catalyzes the chemical reaction
- REDIRECT Template:Chemical reaction
The two substrates of this enzyme are 2-dehydro-D-gluconic acid and an electron acceptor. Its products are 2,5-didehydro-D-gluconic acid and the corresponding reduced acceptor.[1][2][3]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is 2-dehydro-D-gluconate:acceptor 2-oxidoreductase. Other names in common use include ketogluconate dehydrogenase, alpha-ketogluconate dehydrogenase, 2-keto-D-gluconate dehydrogenase, and 2-oxogluconate dehydrogenase. It has 2 cofactors: FAD, and a flavoprotein.
References
- ↑ Enzyme 1.1.99.4 at KEGG Pathway Database.
- ↑ "The oxidation of 2-ketogluconate by a partially purified enzyme from Acetobactor melanogenum". Arch. Biochem. Biophys. 65 (2): 576–8. 1956. doi:10.1016/0003-9861(56)90218-1. PMID 13395514.
- ↑ Shinagawa E; Ameyama M (1982). "2-Keto-d-gluconate dehydrogenase from Gluconobacter melanogenus, membrane-bound". Carbohydrate Metabolism - Part D. Methods Enzymol.. 89. pp. 194–198. doi:10.1016/S0076-6879(82)89034-4. ISBN 978-0-12-181989-7.
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