Biology:Formimidoylglutamate deiminase
From HandWiki
| formimidoylglutamate deiminase | |||||||||
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| Identifiers | |||||||||
| EC number | 3.5.3.13 | ||||||||
| CAS number | 9054-85-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a formimidoylglutamate deiminase (EC 3.5.3.13) is an enzyme that catalyzes the chemical reaction
- N-formimidoyl-L-glutamate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] N-formyl-L-glutamate + NH3
Thus, the two substrates of this enzyme are N-formimidoyl-L-glutamate and H2O, whereas its two products are N-formyl-L-glutamate and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is N-formimidoyl-L-glutamate iminohydrolase. Other names in common use include formiminoglutamate deiminase, and formiminoglutamic iminohydrolase. This enzyme participates in histidine metabolism.
References
- "N-Formimino-L-glutamate iminohydrolase (Pseudomonas sp.)". Methods Enzymol. 17B: 80–84. 1971. doi:10.1016/0076-6879(71)17012-7.
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