Biology:Guanosine phosphorylase
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Short description: Class of enzymes
| guanosine phosphorylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.2.15 | ||||||||
| CAS number | 9030-28-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a guanosine phosphorylase (EC 2.4.2.15) is an enzyme that catalyzes the chemical reaction
- guanosine + phosphate [math]\displaystyle{ \rightleftharpoons }[/math] guanine + alpha-D-ribose 1-phosphate
Thus, the two substrates of this enzyme are guanosine and phosphate, whereas its two products are guanine and alpha-D-ribose 1-phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is guanosine:phosphate alpha-D-ribosyltransferase. This enzyme participates in purine metabolism.
References
- "The phosphorolysis of nucleosides by rabbit bone marrow". The Journal of Biological Chemistry 236: 3043–6. November 1961. PMID 14008731.
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