Biology:Mannosyl-3-phosphoglycerate synthase
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Short description: Class of enzymes
| mannosyl-3-phosphoglycerate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.217 | ||||||||
| CAS number | 393512-63-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a mannosyl-3-phosphoglycerate synthase (EC 2.4.1.217) is an enzyme that catalyzes the chemical reaction
- GDP-mannose + 3-phospho-D-glycerate [math]\displaystyle{ \rightleftharpoons }[/math] GDP + 2-(alpha-D-mannosyl)-3-phosphoglycerate
Thus, the two substrates of this enzyme are GDP-mannose and 3-phospho-D-glycerate, whereas its two products are GDP and 2-(alpha-D-mannosyl)-3-phosphoglycerate.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:3-phosphoglycerate 3-alpha-D-mannosyltransferase. This enzyme is also called MPG synthase.
References
- "Pathway for the synthesis of mannosylglycerate in the hyperthermophilic archaeon Pyrococcus horikoshii. Biochemical and genetic characterization of key enzymes". J. Biol. Chem. 276 (47): 43580–8. 2001. doi:10.1074/jbc.M108054200. PMID 11562374.
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