Biology:Methylecgonone reductase

From HandWiki

Methylecgonone reductase (EC 1.1.1.334, MecgoR (gene name)) is an enzyme with systematic name ecgonine methyl ester:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

ecgonine methyl ester + NADP+ [math]\displaystyle{ \rightleftharpoons }[/math] ecgonone methyl ester + NADPH + H+

The enzyme from the plant Erythroxylum coca participates in the biosynthesis of cocaine.

References

  1. "Plant tropane alkaloid biosynthesis evolved independently in the Solanaceae and Erythroxylaceae". Proceedings of the National Academy of Sciences of the United States of America 109 (26): 10304–9. June 2012. doi:10.1073/pnas.1200473109. PMID 22665766. Bibcode2012PNAS..10910304J. 

External links