Biology:N-carbamoyl-L-amino-acid hydrolase

From HandWiki
N-carbamoyl-L-amino-acid hydrolase
Identifiers
EC number3.5.1.87
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a N-carbamoyl-L-amino-acid hydrolase (EC 3.5.1.87) is an enzyme that catalyzes the chemical reaction

N-carbamoyl-L-2-amino acid (a 2-ureido carboxylate) + H2O [math]\displaystyle{ \rightleftharpoons }[/math] L-2-amino acid + NH3 + CO2

Thus, the two substrates of this enzyme are N-carbamoyl-L-2-amino acid and H2O, whereas its 3 products are L-2-amino acid, NH3, and CO2.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-carbamoyl-L-amino acid amidohydrolase.

References

  • "Purification and characterization of N-carbamoyl-L-amino acid amidohydrolase with broad substrate specificity from Alcaligenes xylosoxidans". Appl. Microbiol. Biotechnol. 43 (6): 1039–43. 1995. doi:10.1007/BF00166922. PMID 8590654.